As at 5.45pm the A49 is closed at Dorrington which is just south of Shrewsbury because of a serious accident.
Hereford United supporters travelling to this evening's game at Shrewsbury may be delayed. Diversions are in operation.
Police say the accident was between a milk tanker and a car. A quantity of milk has split onto the road and needs to be cleaned up.
Update 6.40pm: Road still closed - diversion is taking around 30minutes.
Update: 7.45pm: Road has re-opened.